Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ahvaz Jundishapur University of Medical Sciences

Antifungal Efficacy of Myrtus communis Linn

Sadeghi Nejad, Batool and Erfani Nejad, Maryam and Yusef Naanaie, Sedigheh and Zarrin, Majid (2014) Antifungal Efficacy of Myrtus communis Linn. Jentashapir Journal of Health Research, 5.

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Abstract

Background: The ethanolic extract of Myrtus communis Linn. leaves was assayed in vitro as a growth inhibitor against opportunistic fungi such as Candida and Aspergillus species. Myrtus communis Linn. (Family, Myrtaceae) is an aromatic evergreen shrub or small tree. It is native to the Mediterranean region. Objectives: This study aimed to assess antifungal activity (in vitro) of the ethanolic extracts of Myrtus communis leaves as a growth inhibitor against 24 clinical isolates of Candida, including C. albicans, C. glabrata, and C. tropicalis also three species of Aspergillus, including A. niger, A. flavus, and A. terreus. Materials and Methods: The ethanolic extract of myrtle leaves was prepared by maceration method and minimal inhibitory concentration (MIC) of Myrtus communis leaves extract was determined by agar-well diffusion technique. Amphotericin B and clotrimazole were used as the positive control in this assay. Results: The minimal inhibitory concentration (MICs) values of Myrtus communis leaves extract ranged 0.625-5.0 µg/µL and 5-40 µg/µL against tested Candida spp. and Aspergillus spp., respectively. Conclusions: Results revealed that the ethanolic extract of Myrtus communis leaves have antifungal potency against both pathogenic tested fungi, and it can be used as a natural antifungal agent.

Item Type: Article
Keywords: Keywords: Myrtus; Aspergillus; Candida; Agar; diffusion
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 05 Feb 2018 07:51
Last Modified: 05 Feb 2018 07:51
URI: http://eprints.ajums.ac.ir/id/eprint/11716

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