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Ahvaz Jundishapur University of Medical Sciences

The Frequency of Enterotoxin A Genes and its Association with Antimicrobial Resistance among Staphylococcus aureus Isolates from Clinical Specimens from Patients Admitted to Golestan and Imam Khomeini Hospitals in Ahvaz, Iran

Farajzadeh Sheykh, Ahmad and Ranjbar, Yousef and Meghdadi, Hossein and Alami, Ameneh (2015) The Frequency of Enterotoxin A Genes and its Association with Antimicrobial Resistance among Staphylococcus aureus Isolates from Clinical Specimens from Patients Admitted to Golestan and Imam Khomeini Hospitals in Ahvaz, Iran. Jundishapur Scientific Medical Journal. ISSN 2252-0619

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Abstract

Background and Objectives: Staphylococcus species have higher abundance among isolated isolates from clinical samples. The spices of Staphylococcus aureus which produces enterotoxin A is more viable against host immune defence. The purpose of this study was to assess the relative abundance of entrotoxin A gene and its relation with antimicrobial resistance in isolates of Staphylococcus aureus isolated from clinical samples. Subjects and Methods: All of the isolates of Staphylococcus aureus from sample of patient sent to Golestan and Imam Khomeini hospital clinical labs, were tested biochemically in order to confirm the presence of Staphylococcus aureus strains. Antibiotic resistance of the isolates was assessed by disk diffusion method and PCR method for detection of entrotoxin A gene. Results: Among 222 isolates of Staphylococcus aureus from different clinical samples, 102 (45.94%) of these isolates had entrotoxin A gene. This isolates has been highly resistant to the antibiotics such as Ciprofloxacin, methicillin, gentamicin, erythromycin and clindamycin. Conclusions: The frequency of the Staphylococcus aureus isolates which produces enterotoxin A Gene in Golestan and Imam Khomeini hospitals was high (46.3% and 45.7% Respectively). This samples also have more resistance against antibiotics than the other which has not gene. ►Please cite this paper as: Faraj Zadeh Sheikh A, Ranjbar Y, Meghdadi H, Alami A. The Frequency of Enterotoxin A Genes and its Association with Antimicrobial Resistance among Staphylococcus aureus Isolates from Clinical Specimens from Patients Admitted to Golestan and Imam Khomeini Hospitals in Ahvaz, Iran. Jundishapur Sci Med J 2015; 14(3):301-308.

Item Type: Article
Keywords: Staphylococcus aureus, Entrotoxin A, PCR, Disk diffusion
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 01 May 2018 05:12
Last Modified: 14 Aug 2018 04:17
URI: http://eprints.ajums.ac.ir/id/eprint/13027

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