Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ahvaz Jundishapur University of Medical Sciences

Antimycobacterial activity of partial purified extract of Allium ascalonicum

Amini, Mansour and Segatoleslami, Sepideh and Hashemzadeh, Mohammad (2009) Antimycobacterial activity of partial purified extract of Allium ascalonicum. Jundishapur Journal of Microbiology, 2 (4). pp. 144-147. ISSN 2008-4161

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Introduction and objective: The World Health Organization estimates that about 8 to 10 million new Tuberculosis (TB) cases occur annually worldwide and its incidence is currently increasing. There are two million deaths from TB each year. The plants are an important source of new antimicrobial agents. In this study, antibacterial activity of Allium ascalonicum against Mycobacterium tuberculosis was evaluated. Materials and methods: To extraction antibacterial agent from this plant, 100g of underground root of A. ascalonicum was mixed with 100ml ethyl acetate and shacked gently. Partially purified antibacterial compound was isolated by organic solvents. Antibacterial activity of this fraction against M. tuberculosis was performed using the E test. Results: Shallot extract showed antimycobacterial activity with a minimum inhibitory concentration (MIC) value of 500μg/ml. Conclusion: It is implied that A. ascalonicum extract could be used as an effective antibacterial agent against M. tuberculosis, which is a resistant infection in pulmonary tuberculosis.

Item Type: Article
Keywords: Antibacterial effect, Allium ascalonicum, Mycobacterium tuberculosis
Subjects: R Medicine > R Medicine (General)
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 13 Jun 2015 05:32
Last Modified: 10 Feb 2016 06:49

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