Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ahvaz Jundishapur University of Medical Sciences

Normative data and percentile curves of bone mineral density in healthy Iranian children aged 9-18 years

Jeddi, M. and Roosta, M. J. and Dabbaghmanesh, M. H. and Omrani, G. R. and Ayatollahi, S. M. T. and Bagheri, Z. and Showraki, A. R. and Bakhshayeshkaram, M. (2013) Normative data and percentile curves of bone mineral density in healthy Iranian children aged 9-18 years. Archives of Osteoporosis, 8 (1-2). ISSN 18623522 (ISSN)

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Abstract

We provide the first reference values for bone mineral content and bone mineral density according to age and sex in Iranian children and adolescents. The prevalence of hypovitaminosis D was high, and levels of physical activity were low in our sample. Multiple regression analyses showed age, BMI, and Tanner stage to be the main indicators of bone mineral apparent density. Purpose: Normal bone structure is formed in childhood and adolescence. The potential determinants which interact with genetic factors to influence bone density include gender, nutritional, lifestyle, and hormonal factors. This study aimed to evaluate bone mineral content (BMC) and the bone mineral density (BMD) and factors that may interfere with it in Iranian children. Methods: In this cross-sectional study, 476 healthy Iranian children and adolescents (235 girls and 241 boys) aged 9-18 years old participated. BMC and BMD of the lumbar spine, femoral neck, and total body were measured by dual-energy X-ray absorptiometry using a Hologic Discovery device, and bone mineral apparent density (BMAD) of the lumbar spine and the femoral neck were calculated. Results: We present percentile curves by age derived separately for BMC, BMD, and BMAD of the lumbar spine, left femoral neck, and total body excluding the head for boys and girls. Maximum accretion of BMC and BMD was observed at ages of 11-13 years (girls) and 12-15 years (boys).The prevalence of hypovitaminosis D was high and physical activity was low in our participants. However, in multiple regression analyses, age, BMI, and Tanner stage were the main indicators of BMD and BMAD Conclusion: These normative data aid in the evaluation of bone density in Iranian children and adolescents. Further research to evaluate the evolution of BMD in Iranian children and adolescents is needed to identify the reasons for significant differences in bone density values between Iranian populations and their Western counterparts. © 2013 International Osteoporosis Foundation and National Osteoporosis Foundation.

Item Type: Article
Keywords: Adolescence Bone mineral density Childhood Dual-energy X-ray absorptiometry Exercise Vitamin D adolescent adult anthropometric parameters article bone densitometry bone density bone mineral bone structure child cross-sectional study dual energy X ray absorptiometry female femur neck human imaging system Iran lumbar spine male measurement normal human physical activity priority journal school child young adult
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences
Depositing User: مهندس مهدی شریفی
Last Modified: 01 Jun 2018 11:27
URI: http://eprints.ajums.ac.ir/id/eprint/14675

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