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Ahvaz Jundishapur University of Medical Sciences

Prevalence of Fungal Allergens in Respiratory Allergic Patients in Ahvaz City, Southwest Iran

Assarehzadegan, Mohammad Ali and Shakurnia, Abdol Hussein and Amini, Akram and Shakerinejad, Ghodratollah (2013) Prevalence of Fungal Allergens in Respiratory Allergic Patients in Ahvaz City, Southwest Iran. Jundishapur Journal of Microbiology, 6 (4). pp. 1-5. ISSN 2008-4161

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Background: Fungi are ubiquitous in our environment and they are one of the important causes of allergic diseases. Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis. Objectives: The purpose of this study was to determine the prevalence of skin reactivity to common fungal allergens and total IgE in patients with allergic rhinitis in Ahvaz city. Patients and Methods: In this cross sectional study, 295 volunteers with the signs and symptoms of allergic diseases who referred to the Khuzestan Jahad Daneshgahi Medical Center in Ahvaz during 2010 were investigated. All patients were subjected to skin prick test (SPT) with common allergenic extracts. Data were analyzed by SPSS-18 software using Chi square test. Results: Seventy subjects, comprising 23.7% of the study group had positive skin test to at least one of the fungal allergens. The prevalence rate of sensitivity to fungal allergens was as follow: Cephalosporin 11.5%; mold mix 9.8%; Penicillium mix 9.5%; Alternaria mix 8.1%; and Aspergillus 5.1%. Mean total IgE in patients with SPT was significantly higher than in patients without any positive skin prick test (251 vs. 125 IU/mL, P = 0.001). There was no statistical difference in the prevalence of sensitization to these allergens between two sexes; whereas, 15-35 age groups had significantly higher rates of allergy to fungal allergens (P = 0.047). Conclusions: Fungal sensitization is a relatively common finding among patients with allergic rhinitis. Elimination or reduction of mold exposure in allergic patients is of special consideration and measures to reduce environmental factors which facilitate mold growth and proliferation are very important.

Item Type: Article
Keywords: Allergy; Fungal Allergen; Skin Prick Test
Subjects: R Medicine > R Medicine (General)
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 30 May 2015 09:33
Last Modified: 10 Feb 2016 06:08

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