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Ahvaz Jundishapur University of Medical Sciences

DISTRIBUTION MODEL OF SERUM LIPOPROTEIN (A) CONCENTRATION IN A HEALTHY IRANIAN POPULATION LIVING IN KHUZESTAN PROVINCE, IRAN. 2004.

Taha Jalali, M (2007) DISTRIBUTION MODEL OF SERUM LIPOPROTEIN (A) CONCENTRATION IN A HEALTHY IRANIAN POPULATION LIVING IN KHUZESTAN PROVINCE, IRAN. 2004. Jundishapur Journal of Natural Pharmaceutical Products, 2 (2). pp. 111-115. ISSN 2228-7876

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Abstract

Based on many epidemiologic studies, lipoprotein (a) [Lp(a)] with its peculiar structural properties was proposed as independent, risk factor for cardiovascular and thrombotic cerebral events. Since, genetic effect plays a paramount role in determining the final serum concentration, the reference serum concentration for this particle exhibits a wide variation among different population and even within a family. In order to prevent its pathologic effect which has been related to its high serum concentration it is a prerequisite to determine its serum concentration distribution model in a particular population before any therapeutic measure is arranged. To accomplish this goal a group of 350 healthy volunteers living in southern province of Khuzestan, Iran, were analyzed for their Lp (a) serum concentration employing and isoform- insensitive ELISA technique. The obtained result showed skewed distribution toward lower concentration ranging from 3 to 53 mg/dL with mean, median and standard deviation as 14.42, 12.0 and 8.46 mg/dL.

Item Type: Article
Keywords: Lipoprotein (a), Healthy population, Skewed distribution, Reference range.
Subjects: R Medicine > R Medicine (General)
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 23 Jun 2015 21:04
Last Modified: 10 Feb 2016 06:51
URI: http://eprints.ajums.ac.ir/id/eprint/1708

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