Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ahvaz Jundishapur University of Medical Sciences

Incidence and Contributing Factors of Persistent Hyperglycemia at 6-12 Weeks Postpartum in Iranian Women with Gestational Diabetes: Results from LAGA Cohort Study

Nouhjah, S. and Shahbazian, H. and Shahbazian, N. and Jahanshahi, A. and Jahanfar, S. and Cheraghian, B. (2017) Incidence and Contributing Factors of Persistent Hyperglycemia at 6-12 Weeks Postpartum in Iranian Women with Gestational Diabetes: Results from LAGA Cohort Study. Journal of Diabetes Research. ISSN 2314-6745

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Abstract

Background. A history of gestational diabetes is an important predictor of many metabolic disturbances later in life. Method. Life after gestational diabetes Ahvaz Study (LAGAs) is an ongoing population-based cohort study. Up to February 2016, 176 women with gestational diabetes underwent a 75 g oral glucose tolerance test (OGTT) at 6-12weeks postpartum in Ahvaz (southwestern of Iran). Gestational diabetes was diagnosed according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and the American Diabetes Association (ADA) criteria applied for diagnosis of postpartum prediabetes and diabetes. Univariate and multivariate regression analysis were done. Results. Overall incidence of early postpartum glucose intolerance was 22.2 (95 CI, 16.3-29.0), 17.6 prediabetes (95 CI, 12.3-24.1) and 4.5 diabetes (95 CI, 2.0-8.8). Independent risk factors for glucose intolerance were FPG >= 100 at the time of OGTT (OR 3.86; 95 CI; 1.60-9.32), earlier diagnosis of GDM (OR 0.92; 95 CI; 0.88-0.97), systolic blood pressure (OR 1.02; 95 CI; 1.002-1.04), and insulin or metformin therapy (OR 3.14; 95 CI; 1.20-8.21). Conclusion. Results determined a relatively high rate of glucose intolerance at 6-12 weeks after GDM pregnancy. Early postpartum screening of type 2 diabetes is needed particularly in women at high risk of type 2 diabetes.

Item Type: Article
Keywords: glucose-tolerance postpartum insulin-resistance iadpsg criteria pregnant-women latino women risk-factors mellitus prevalence metaanalysis predictors
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences
Depositing User: مهندس مهدی شریفی
Last Modified: 01 Jun 2018 13:09
URI: http://eprints.ajums.ac.ir/id/eprint/17647

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