Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ahvaz Jundishapur University of Medical Sciences

The effect of grape seed extract (GSE) on spatial memory in aged male rats

Sarkaki, A. and Farbood, Y. and Badavi, M. (2007) The effect of grape seed extract (GSE) on spatial memory in aged male rats. Pakistan Journal of Medical Sciences, 23 (4). pp. 561-565. ISSN 1682024X (ISSN)

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Objective: To test the effect of GSE on spatial memory in aged male rats. Methodology: We hypothesized that ingestion of polyphenols-enriched preparation such as GSE would be manifested as cognitive-enhancement that would be consistent with neuroprotection in aged rats. Aged male rats were divided into two groups (control and GSE treated). Control rats received normal saline and treated rats received GSE (100mg/kg) by oral gavage for 30 days. They trained in Morris water maze. Results: Our data showed that administration of grape seed extract to aged rats improves memory retention in water maze performance. Conclusion: Based on the results of the Morris water maze tests using aged rats, we found that GSE had remarkable cognitive-enhancing effect.

Item Type: Article
Keywords: Aging GSE Memory Rat Water maze grape seed extract plant extract polyphenol derivative unclassified drug animal experiment article cognition controlled study grape male maze test neuroprotection nonhuman spatial memory
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences
Depositing User: مهندس مهدی شریفی
Last Modified: 01 Jun 2018 13:14
URI: http://eprints.ajums.ac.ir/id/eprint/19511

Actions (login required)

View Item View Item