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Ahvaz Jundishapur University of Medical Sciences

Antibacterial Activity of Silver Nanoparticles and Their Combination with Zataria multiflora Essential Oil and Methanol Extract

Sheikholeslami, Shirin and Mousavi, Seyyedeh Elaheh and Ahmadi Ashtiani, Hamid Reza and Hosseini Doust, Seyed Reza and Mahdi Rezayat, Seyed (2016) Antibacterial Activity of Silver Nanoparticles and Their Combination with Zataria multiflora Essential Oil and Methanol Extract. Jundishapur Journal of Microbiology, 9 (10). ISSN 2008-3645

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Official URL: http://doi.org/10.5812/jjm.36070

Abstract

Background: Against a variety of antimicrobial resistant pathogens, the scientists attempted substitution of antimicrobial medicine with various nanoparticles and plant-based antibacterial substances. Objectives: The aim of this study was to assess the antibacterial effects of silver nanoparticles solely and in combination with Zataria multiflora essential oil and methanolic extract on some photogenic bacteria. Methods: Minimum inhibitory concentrations (MICs) and fractional inhibitory concentrations (FICs) of plant essential oil, methanolic extract, and silver nanoparticles against bacteria were evaluated using the broth microdilution method and check board microtiter assays. Results: The results of the experiment showed that the MIC and minimal bacterial concentration (MBC) values of Ag-NPs against all strains were in the range of 15.625 - 500 µg/mL, and values for the essential oil and plant extract were in the range of 1.56 - 100 mg/mL. Conclusions: Silver nanoparticles were observed to have additive effects with essential oil against Staphylococcus epidermidis and S. aureus. The obtained results suggest the need for further investigations of the antibacterial effects of the combination of silver nanoparticles with other plant extracts and essential oils.

Item Type: Article
Keywords: Nanoparticles; Silver; Antibacterial Susceptibility; Essential Oil; Plant Extracts; Bacteria
Subjects: R Medicine > R Medicine (General)
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 14 Nov 2016 06:03
Last Modified: 14 Nov 2016 06:03
URI: http://eprints.ajums.ac.ir/id/eprint/2635

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