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Ahvaz Jundishapur University of Medical Sciences

Comparison of Epidemiological, Clinical, Laboratory and Radiological Features of Hospitalized Diabetic and Non-Diabetic Patients With Pulmonary Tuberculosis at Razi Hospital in Ahvaz

Alavi, Seyed Mohammad and Khoshkho, Mohammad Mehdi and Salmanzadeh, Shokrolah and Eghtesad, Mehdi (2014) Comparison of Epidemiological, Clinical, Laboratory and Radiological Features of Hospitalized Diabetic and Non-Diabetic Patients With Pulmonary Tuberculosis at Razi Hospital in Ahvaz. Jundishapur Journal of Microbiology, 7 (9). pp. 1-5. ISSN 2008-4161

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Abstract

Background: Diabetes mellitus (DM) due to suppressive effect on cellular immunity can impact on progression of tuberculosis (TB). Objectives: The aim of this study was to investigate the impact of DM on the epidemiological, clinical and para clinical aspects of pulmonary TB. Patients and Methods: The information of 148 admitted pulmonary TB patients in infectious ward of Razi hospital in Ahvaz from 2009 to 2010 was extracted from their medical files. The patients were divided into two groups as TB with DM (n = 36) and TB without DM (n = 112). The related data on epidemiology, signs, symptoms, radiology and sputum smear examination in both groups were compared in SPSS 16 by using chi squared test. Results: The mean age of TB with DM patients was higher TB without DM patients (56.6 ± 12.7 vs. 44.8 ± 18.3; respectively, P = 0.006). Whereas cough, night sweating, fever and weigh loss was not statistically different, sputum, hemoptysis and dyspnea was more prominent in TB with DM (69.4%, 33.4%, 44.5% vs. 36.6%, 9.8%, 20.5%; P = 0.005, P = 0.001, P = 0.005, respectively). In chest x-ray, cavitation and reticulonodular pattern was more frequent in TB with DM (55.5%, 22.2% vs. 31.2%, 8% - P = 0.008, P = 0.02, respectively). The rate of sputum smear positivity in TB with DM and TB without DM was 66.6% and 47.3%, respectively (P = 0.03). Conclusions: According to the results of this study, in approach to every DM cases suffering of respiratory symptoms such as productive cough, hemoptysis and dyspnea in association with cavitation or miliary mottling in chest x-ray, pulmonary TB should be considered at the top of the differential diagnosis list.

Item Type: Article
Keywords: Pulmonary tuberculosis; Diabetes Mellitus; Epidemiology; Clinical Features; Radiology
Subjects: R Medicine > R Medicine (General)
Depositing User: آقای بهرام سوسنی غریب وند
Date Deposited: 01 Jun 2015 08:44
Last Modified: 10 Feb 2016 06:17
URI: http://eprints.ajums.ac.ir/id/eprint/379

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